Endocrine Abstracts

The endogenous thyroid hormone metabolite 3,5-diiodothyronine (3,5-T2) has attracted attention as a metabolically active substance modulating metabolism via classical thyroid hormone (TH) receptor-dependent and rapid plasma membrane, cytosolic and mitochondrial signaling pathways. Accordingly, 3,5-T2 has been proposed as a potential hypolipidaemic agent without inducing thyromimetic effects and is frequently used as illicit weight-reducing agent. The objective of the present s...